Lissencephaly

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Lissencephaly - A Brain Flawed

We present a case report of a twelve-day old child suffering from seizures, in which magnetic resonance imaging (MRI) established the diagnosis of Lissencephaly. Although the causes of this disease entity are manifold, MRI can reveal stigmata of antenatal maternal infections in the child. In such a scenario, cytomegalovirus (CMV) is an important offender. In this article we discuss the pathogen...

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INDIAN PEDIATRICS Lissencephaly

Lissencephaly means smooth brain, i.e., brain without convolutions or gyri. Miller in (1963) and later Dieker in 1969 described a specific pattern of malfor mations, one feature of which was lissencephaly(l,2). They emphasized that this should be called lissencephaly syndrome because of the association of polydactyly, unusual facial appearanc es, malformation of the heart, kidneys and other org...

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MR of lissencephaly.

MR imaging was performed on a 2-year-old girl whose history included low Apgar score, hypotonicity, and myoclonic seizures at birth . Her psychomotor and growth development were retarded. She had mild microcephaly and was hypotonic. Electroencephalography showed generalized epileptogenic activity. MR imaging was performed on a 0.5-T scanner. T1-weighted images, SE 500/30, performed in the axial...

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Lissencephaly in a Pekingese

A 1-year-old neutered male Pekingese was presented for evaluation and further treatment of cluster seizures. The dog had behavioral abnormalities, and a prosencephalic lesion was suspected following neurological examination. The dog showed signs of learning difficulty. Magnetic resonance imaging of the brain revealed a remarkably smooth cerebral cortex with a reduced number of gyri, as well as ...

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Lissencephaly, generic term

Key-words Definition/Classification Etiology Classic lissencephalies Lissencephaly variants Cobblestone lissencephalies Bibliography

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ژورنال

عنوان ژورنال: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques

سال: 1976

ISSN: 0317-1671,2057-0155

DOI: 10.1017/s0317167100025981